Please query the genome coordinates or gene symbols in the search bar to navigate to a region of your interest. For examples: "chr1:1407902-1587442" ; "SOD1"

The predicted branchpoints shown in the Integrative Genomics Viewer (IGV) were identified using SVM-bpfinder [1] with the highest score and the experimental-based branchpoints were collected from these studies [2-5]:

1. Corvelo, A., Hallegger, M., Smith, C. W., & Eyras, E. (2010). Genome-wide association between branch point properties and alternative splicing. PLoS computational biology, 6(11), e1001016. (doi: 10.1371/journal.pcbi.1001016.)


2. Mercer TR, Clark MB, Andersen SB, Brunck ME, Haerty W, Crawford J, Taft RJ, Nielsen LK, Dinger ME, Mattick JS. Genome-wide discovery of human splicing branchpoints. Genome Res. 2015 Feb;25(2):290-303. (doi: 10.1101/gr.182899.114. Epub 2015 Jan 5. PMID: 25561518; PMCID: PMC4315302.)


3. Taggart AJ, Lin CL, Shrestha B, Heintzelman C, Kim S, Fairbrother WG. Large-scale analysis of branchpoint usage across species and cell lines. Genome Res. 2017 Apr;27(4):639-649. (doi: 10.1101/gr.202820.115. Epub 2017 Jan 24. PMID: 28119336; PMCID: PMC5378181.)


4. Pineda JMB, Bradley RK. Most human introns are recognized via multiple and tissue-specific branchpoints. Genes Dev. 2018 Apr 1;32(7-8):577-591. (doi: 10.1101/gad.312058.118. Epub 2018 Apr 17. PMID: 29666160; PMCID: PMC5959240.)


5. Zeng Y, Fair BJ, Zeng H, Krishnamohan A, Hou Y, Hall JM, Ruthenburg AJ, Li YI, Staley JP. Profiling lariat intermediates reveals genetic determinants of early and late co-transcriptional splicing. Mol Cell. 2022 Dec 15;82(24):4681-4699.e8. (doi: 10.1016/j.molcel.2022.11.004. Epub 2022 Nov 25. PMID: 36435176; PMCID: PMC10448999.)